Currently, missing teeth can’t be regrown. Options such as dental implants, bridges, and dentures can act as artificial replacements for missing teeth. The right option for you will depend on how much decay and damage has occurred, how many teeth you’ve lost, your overall health, and your budget.
Stem cell dental implants work towards regrowing the missing teeth in the affected person’s mouth. The problem with human teeth is that throughout a person’s lifetime, they only get two sets of teeth (baby teeth are lost at the age of 12 or 13 while adult teeth need to last till lifetime).
Toregem Biopharma, funded by Kyoto University, is expected to begin clinical trials on healthy adults in around July 2024 to confirm the drug’s safety, after the team succeeded in growing new teeth in mice in 2018. The first patients will be receiving the drug intravenously in September of this year. If the trial is successful, the researchers hope the drug will become available for all forms of toothlessness sometime around 2030.
To learn more, visit: https://www.japantimes.co.jp/news/2023/09/24/japan/science-health/japan-pharma-grows-new-teeth/
In what could be the weirdest news of the week, Japanese researchers may have found a way for humans to grow back their teeth…
World’s First Tooth-Regrowing Drug Enters Human Trials A revolutionary tooth-regrowing drug, targeting the USAG-1 gene, has entered human trials following successful tests in mice and ferrets. Developed by scientists at Kyoto University and the University of Fukui, this monoclonal antibody treatment shows promising results for tooth regeneration.
By inhibiting the USAG-1 gene, the drug stimulates tooth growth without significant side effects, offering hope to adults suffering from congenital tooth loss. Lead researcher Katsu Takahashi highlights the drug’s efficacy, with a single administration proving sufficient to generate a whole tooth in animal models.
This breakthrough paves the way for a new era in dental medicine, potentially replacing conventional implants with cell-free molecular therapy.
Scientists at the University of Washington are taking stem cell research to a new level. They’re working to regenerate something people often take for granted: our teeth.
A multidisciplinary group of researchers from UW have unlocked the first steps toward regenerating teeth. Researchers are sharing their findings at the lab affiliated with UW Medicine’s Institute for Stem Cell and Regenerative Medicine.
What appeared to be just a dark blob under a microscope, has the potential to restore human teeth, according to their research. Known as “organoids,” they are the 3D, cellular forms that mimic the organs in our body, including teeth.